HO/02/10 - Skin Inflammation
HO/02/10 is a topical therapeutic under development, for the treatment of skin inflammation seen in various dermatological diseases such as psoriasis.
Psoriasis is a chronic, autoimmune skin disease characterized by scaling and inflammation of the skin, usually in the form of thick, red, scaly patches or lesions, which can be either localized or cover the entire body. These patches, which are sometimes referred to as plaques, usually itch or feel sore, and can cause significant physical discomfort and some disability. Psoriasis can affect quality of life to an extent similar to other chronic diseases such as diabetes, heart disease and depression. According to the NIH, Psoriasis affects between 5.8-7.5 million Americans and 2%-3% of Western populations.
Mode of Action
HO/02/10's multi-phasic mode of action is to inhibit the immune response, thereby reducing the inflammatory process, as well as to normalize skin cell differentiation and proliferation, thus reducing redness and scaling.