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Bicalutamide for Transgender Women: What You Need to Know

Updated: 23 hours ago


HRT FOR GENDER REAFFIRMATION


Bi-calutamide and feminizing hormone therapy


Bicalutamide is an anti-androgen drug which means that it blocks the effect of androgenic hormones such as testosterone and DHT. The important thing to understand is that bicalutamide does not lower testosterone levels, it simply blocks the effect of testosterone on tissues. In many cases, Testosterone levels initially increase after starting this medication however, that is nothing to be concerned about. Testosterone levels start declining over time, this change happens much more rapidly if you're also taking estrogen and progesterone in addition to bicalutamide


Bicalutamide is most commonly used for treating men with prostate cancer


Off-label uses:

  • Puberty blocker

  • Feminization therapy

  • Androgenic Alopecia in females

  • Acne Reduction

Today primarily will be focusing on bicalutamide use in transgender females