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How to treat symptoms of post-orgasmic illness syndrome [POIS]

Updated: 22 hours ago

What is Post-orgasmic illness syndrome?

When male sexual health is discussed mostly it is about men with erectile dysfunction, premature ejaculation, and delayed ejaculation. Postorgasmic illness syndrome (POIS) is a rare and poorly understood medical condition in which people experience a range of physical, cognitive, and emotional symptoms following sexual activity, particularly orgasm that can significantly affect the quality of life and can cause significant emotional distress. Most men have such extreme fatigue post-ejaculation that they start to avoid sexual activity completely.

post-orgasmic illness syndrome [POIS]

When do symptoms appear?

The symptoms usually begin within minutes to hours after orgasm and can last for several days.

What are the symptoms of Postorgasmic illness syndrome?

Symptoms of POIS can vary widely from person to person, but may include:

  • Flu-like symptoms such as fatigue, fever, chills, muscle aches, and headaches

  • Cognitive symptoms such as brain fog, difficulty concentrating, memory problems, and irritability

  • Allergic-like symptoms such as itching, sneezing, and nasal congestion

  • Gastrointestinal symptoms such as diarrhea and abdominal pain

  • Skin symptoms such as rash and flushing